Invention Grant
- Patent Title: Glyco-engineered antibodies
- Patent Title (中): 糖精工程抗体
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Application No.: US12373268Application Date: 2007-07-11
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Publication No.: US09051577B2Publication Date: 2015-06-09
- Inventor: Manfred Schuster , Ralf Kircheis , Andreas Nechansky , Wolfgang Jost , Gilbert Gorr
- Applicant: Manfred Schuster , Ralf Kircheis , Andreas Nechansky , Wolfgang Jost , Gilbert Gorr
- Applicant Address: DE Freiburg
- Assignee: GREENOVATION BIOTECH GMBH
- Current Assignee: GREENOVATION BIOTECH GMBH
- Current Assignee Address: DE Freiburg
- Agency: Norton Rose Fulbright US LLP
- Priority: EP06450095 20060711
- International Application: PCT/EP2007/006123 WO 20070711
- International Announcement: WO2008/006554 WO 20080117
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07K16/00 ; C07K16/28

Abstract:
The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that • the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and • at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.
Public/Granted literature
- US20090291078A1 GLYCO-ENGINEERED ANTIBODIES Public/Granted day:2009-11-26
Information query
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