Invention Grant
- Patent Title: Heat-resistant newcastle disease virus live vaccine vector system and use thereof
- Patent Title (中): 耐热新城疫病毒活疫苗载体系统及其应用
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Application No.: US13924812Application Date: 2013-06-24
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Publication No.: US09051584B2Publication Date: 2015-06-09
- Inventor: Guoyuan Wen , Huabin Shao , Jun Yang , Honglin Wang , Qingping Luo , Rongrong Zhang , Diyun Ai , Ling Luo , Yu Shang , Jing Guo , Chen Chen
- Applicant: Institute of Animal Husbandry and Veterinary Science, Hubei Academy of Agricultural Sciences
- Applicant Address: CN Wuhan, Hubei
- Assignee: INSTITUTE OF ANIMAL HUSBANDRY AND VETERINARY SCIENCES, HUBEI ACADEMY OF AGRICULTURAL SCIENCES
- Current Assignee: INSTITUTE OF ANIMAL HUSBANDRY AND VETERINARY SCIENCES, HUBEI ACADEMY OF AGRICULTURAL SCIENCES
- Current Assignee Address: CN Wuhan, Hubei
- Agency: Morris, Manning & Martin, LLP
- Agent Tim Tingkang Xia, Esq.
- Priority: CN201310090099 20130320
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N7/00
Abstract:
A heat-resistant NDV live vaccine vector system includes a transcription plasmid, three helper plasmids, and host cells. The transcription plasmid is constructed by through cloning complete genomic cDNA of a heat-resistant NDV vaccine strain to a pBR322 vector. The three helper plasmids are constructed by cloning sequences coding nucleoprotein (NP), phosphoprotein, large polymerase protein of a heat-resistant NDV vaccine strain respectively to pcDNA3.1 vectors. A recombinant NDV artificially obtained by cotransfacting host cells with the transcription plasmid and the three helper plasmids shows heat-resistance.
Public/Granted literature
- US20140287496A1 HEAT-RESISTANT NEWCASTLE DISEASE VIRUS LIVE VACCINE VECTOR SYSTEM AND USE THEREOF Public/Granted day:2014-09-25
Information query
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