Invention Grant
US09051620B2 Pharmaceutical angiogenic composition including a microRNA-382 activator
有权
包含微小RNA-382激活剂的药物血管发生组合物
- Patent Title: Pharmaceutical angiogenic composition including a microRNA-382 activator
- Patent Title (中): 包含微小RNA-382激活剂的药物血管发生组合物
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Application No.: US14240530Application Date: 2012-08-29
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Publication No.: US09051620B2Publication Date: 2015-06-09
- Inventor: You Mie Lee
- Applicant: You Mie Lee
- Applicant Address: KR
- Assignee: Kyungpook National University Industry—Academic Cooperation Foundation
- Current Assignee: Kyungpook National University Industry—Academic Cooperation Foundation
- Current Assignee Address: KR
- Agency: Rivers de Law LLP
- Priority: KR10-2011-0086986 20110830; KR10-2012-0094792 20120829
- International Application: PCT/KR2012/006909 WO 20120829
- International Announcement: WO2013/032230 WO 20130307
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113
Abstract:
The present invention relates to an angiogenic composition, and more particularly, to a pharmaceutical angiogenic composition including a microRNA-382 activator. The inventors of the present invention have confirmed that microRNA-382, the expression of which is elevated in stomach cancer cells in a low oxygen environment, affects the promotion of angiogenesis. Therefore, provided in the present invention is the pharmaceutical angiogenic composition which includes the microRNA-382 activator, which is angiogenic and thus promotes cell proliferation, and can be valuably used in treating injuries, ischemic myocardial infarctions, or foot ischemia.
Public/Granted literature
- US20140227245A1 Pharmaceutical Angiogenic Composition Including a MicroRNA-382 Activator Public/Granted day:2014-08-14
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