A system for sound isolation. The system is configured to acoustically isolate a gypsum board support channel from a frame member. The system may comprise: a sound isolation clip and fastener, wherein the sound isolation clip comprises a slit configured for mounting onto a flange of a support channel and a fastener hole for securing the fastener and sound isolation clip onto the flange of the support channel. The fastener may be a screw and may comprise a wafer head and shank with a threaded portion and a smooth portion. The threaded portion is used to fasten and secure the mounting screw, sound isolation clip, and support channel onto a wallboard panel and support frame. The smooth portion is used to allow the sound isolation clip to freely move when engaged with the support channel and uniformly distribute the static dead load into the sound isolation clip.