Invention Grant
- Patent Title: Osmolyte mixture for protein stabilization
- Patent Title (中): Osmolyte混合物用于蛋白质稳定
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Application No.: US12870236Application Date: 2010-08-27
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Publication No.: US09052323B2Publication Date: 2015-06-09
- Inventor: Mark T. Fisher , Hiroo Katayama
- Applicant: Mark T. Fisher , Hiroo Katayama
- Applicant Address: US KS Lawrence
- Assignee: The University of Kansas
- Current Assignee: The University of Kansas
- Current Assignee Address: US KS Lawrence
- Agency: Maschoff Brennan, PLLC
- Main IPC: C40B30/10
- IPC: C40B30/10 ; G01N33/68 ; C12N9/96
Abstract:
An osmolyte composition comprising 4 M glycerol and 4M urea for stabilizing previously transient protein folding intermediates as long-lived stable forms. A method to search for other possible stabilizing osmolyte mixtures using a screening array is also provided. These additional osmolyte mixtures may complement or augment the successful 4M glycerol/4 M urea mixture.
Public/Granted literature
- US20110053795A1 Osmolyte Mixture for Protein Stabilization Public/Granted day:2011-03-03
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