The present invention is directed towards systems and methods for mixed-mode load balancing by a virtual server in a network supporting a plurality of internet protocols. In various embodiments, a mixed-mode virtual server receives service requests based on two or more internet layer protocols. The mixed-mode virtual server is configured to detect an IP address type of the client issuing the service request, and identify the internet protocol of the service request based on the detected IP address type. The mixed-mode virtual server can then forward the request to a server supporting the identified internet protocol. In this manner, the mixed-mode virtual server can bind load balance servers supporting a plurality of internet protocols.