A load balancer that is able to detect and mitigate a Denial of Service (DOS) attack. The load balancer is placed in the flow path of network data packets that are destined for one or more tenant addresses. The load balancer analyzes performance parameters regarding the network data packets that are destined for the one or more tenant addresses and are received at the load balancer. The performance parameters describe network data packet flow to the tenant addresses. The load balancer detects, based on the analysis of the performance parameters, that one or more of the tenant addresses are being subjected to a DOS attack. The load balancer performs a mitigation operation to isolate the one or more tenant addresses being subjected to the DOS attack.