Techniques for selecting radios and mapping applications to radios on a wireless device are described. The wireless network may have at least one application that is active and a plurality of radios that are available for use. In one design, the wireless device determines requirements of the at least one application, which may be related to throughput, latency, jitter, etc. The wireless device selects at least one radio among the plurality of radios based on the requirements of the at least one application and possibly other factors. The wireless device determines a mapping of the at least one application to the at least one radio based on the requirements of the at least one application, the performance of the at least one radio, and/or other factors. The wireless device maps the at least one application to the at least one radio based on the mapping.