A high efficiency thermal printing system, comprising: a donor ribbon having donor material; a receiver medium; a test pattern to be printed on the receiver medium using the donor ribbon; a print head, a sensor, and a processor is disclosed. The present invention is adapted to print the test pattern on the receiver medium by heating the donor ribbon to cause the donor material to transfer from the donor ribbon onto the receiver medium, thereby depleting donor material on the donor ribbon. Moreover, the sensor is adapted to measure a depletion amount of the donor material on the donor ribbon after printing the test pattern, and the processor is adapted to calibrate the thermal printing system by adjusting a lookup table in response to the measured depletion amount of donor material.