Interactive custom printed order placement and fulfillment systems and methods for placing, selling, accepting, proofing, transmitting, producing, servicing, and delivering orders for printed products including individualized or personalized information in time-efficient ways. Video conferencing technicians can provide direct access to professional, expert, and knowledgeable help. The interactive custom printed order fulfillment systems and methods further provide opportunities for targeted up-sells, cross-promotion, advertising, marketing, and information management to benefit those placing orders, those facilitating or brokering orders, and those producing and delivering orders, thereby increasing information efficiency.