A method and apparatus for controlling enhanced dedicated channel (E-DCH) transmissions are disclosed. A plurality of primary absolute grants are received, wherein the plurality of primary absolute grants are associated with a TTI. At least one relative grant is received for E-DCH transmission, wherein the at least one relative grant is associated with the TTI. At least one serving grant for E-DCH transmission is determined. A H-ARQ process is identified for use for the TTI. It is determined whether the identified H-ARQ process is available for scheduled data and whether scheduled data is allowed to be transmitted in the TTI based at least on the identified H-ARQ process. On a condition that the identified H-ARQ process is available for scheduled data and scheduled data is allowed to be transmitted in the TTI, scheduled data is allocated for transmission in the TTI.