Invention Grant
US09072676B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives
有权
环己基氨基甲酸酯化合物作为皮肤和/或发亮活性物质
- Patent Title: Cyclohexyl carbamate compounds as skin and/or hair lightening actives
- Patent Title (中): 环己基氨基甲酸酯化合物作为皮肤和/或发亮活性物质
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Application No.: US13699494Application Date: 2010-05-25
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Publication No.: US09072676B2Publication Date: 2015-07-07
- Inventor: Gabriele Vielhaber , Heiko Oertling , Nicole Titze , Claudia Gömann , Rahim Brodhage
- Applicant: Gabriele Vielhaber , Heiko Oertling , Nicole Titze , Claudia Gömann , Rahim Brodhage
- Applicant Address: DE Holzminden
- Assignee: SYMRISE AG
- Current Assignee: SYMRISE AG
- Current Assignee Address: DE Holzminden
- Agency: Novak Druce Connolly Bove + Quigg LLP
- International Application: PCT/EP2010/057115 WO 20100525
- International Announcement: WO2010/122178 WO 20101028
- Main IPC: A61Q5/08
- IPC: A61Q5/08 ; A61Q19/02 ; A61K8/44 ; A61K8/42 ; C08L5/00 ; A61K31/27 ; A61K45/06 ; A61Q17/04

Abstract:
The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as skin and/or hair lightening (whitening) actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4 -alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR1R2, wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.
Public/Granted literature
- US20130156710A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES Public/Granted day:2013-06-20
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