Invention Grant
US09072713B2 Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function
有权
Perlecan域V保护，修复和恢复缺血性脑卒中损伤和运动功能
- Patent Title: Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function
- Patent Title (中): Perlecan域V保护，修复和恢复缺血性脑卒中损伤和运动功能
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Application No.: US13175518Application Date: 2011-07-01
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Publication No.: US09072713B2Publication Date: 2015-07-07
- Inventor: Gregory J. Bix
- Applicant: Gregory J. Bix
- Applicant Address: US TX College Station
- Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
- Current Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
- Current Assignee Address: US TX College Station
- Agency: Saliwanchik Lloyd & Eisenschenk
- Main IPC: C07K1/00
- IPC: C07K1/00 ; A61K38/02 ; A61K31/727 ; A61K38/20 ; A61K38/17 ; A61K45/06 ; C07K16/28
Abstract:
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for the treatment of stroke, TBI or SCI. DV is also referred to as endorepellin in the art. This application also provides compositions and combination therapies for the treatment of stroke, TCI and/or SCI. Another aspect of the invention provides methods of restoring motor function in subjects having neurological damage arising from a stroke, TBI or SCI.
Public/Granted literature
- US20120003180A1 PERLECAN DOMAIN V PROTECTS, REPAIRS AND RESTORES ISCHEMIC BRAIN STROKE INJURY AND MOTOR FUNCTION Public/Granted day:2012-01-05
Information query
