The present invention relates to an iontophoresis patch integrated with a battery, more specifically to an iontophoresis patch integrated with a battery which adopts the principle of iontophoresis as a means for infiltrating a substance of interest such as a medication or a cosmetic substance into skin. The iontophoresis patch of the invention comprises: a variable-shape substrate; a first electroconductive layer coming into contact with the substrate; a first electrode layer coming into contact with a part of the first electroconductive layer; a second electroconductive layer which comes into contact with the substrate and which is disposed on the same as the first electroconductive layer; a collector coming into contact with the second electroconductive layer; an electroconductive adhesive coming into contact with the second electroconductive layer and with the collector; a second electrode layer coming into contact with the collector and having a polarity opposite to that of the first electrode layer; an ion-conductive polymer electrolyte disposed between the first electrode layer and the second electrode layer; and an adhesive for sealing the ion-conductive polymer electrolyte.