Invention Grant
US09073830B2 Compound for inhibiting 11β-hydroxy steroid dehydrogenase 1, and a pharmaceutical composition comprising the same
有权
用于抑制11β-羟基类固醇脱氢酶1的化合物和包含其的药物组合物
- Patent Title: Compound for inhibiting 11β-hydroxy steroid dehydrogenase 1, and a pharmaceutical composition comprising the same
- Patent Title (中): 用于抑制11β-羟基类固醇脱氢酶1的化合物和包含其的药物组合物
-
Application No.: US14237060Application Date: 2012-08-06
-
Publication No.: US09073830B2Publication Date: 2015-07-07
- Inventor: Inhee Lee , Doohyeok Pyeon , Myounghyeon Shin , Jeongun Hwang , Changmin Park , Sehoan Kim , Heeil Chae , Soonyoung Moon , Soyoun Kim , Jaekeol Rhee
- Applicant: Inhee Lee , Doohyeok Pyeon , Myounghyeon Shin , Jeongun Hwang , Changmin Park , Sehoan Kim , Heeil Chae , Soonyoung Moon , Soyoun Kim , Jaekeol Rhee
- Applicant Address: KR Cheonan-si, Chungcheongnam-do
- Assignee: Hyundai Pharm Co., Ltd.
- Current Assignee: Hyundai Pharm Co., Ltd.
- Current Assignee Address: KR Cheonan-si, Chungcheongnam-do
- Agency: Vorys, Sater, Seymour and Pease LLP
- Agent Mihsun Koh
- Priority: KR10-2011-0077913 20110804
- International Application: PCT/KR2012/006216 WO 20120806
- International Announcement: WO2013/019091 WO 20130207
- Main IPC: C07C311/29
- IPC: C07C311/29 ; C07D213/71 ; C07D215/36 ; C07C311/20 ; C07C311/19 ; A61K31/18 ; C07C311/13 ; C07C311/39
Abstract:
Disclosed are a novel compound or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including the same for inhibiting human 11-β-hydroxy steroid dehydrogenase type 1 (11β-HSD1). The disclosed compound and the pharmaceutical composition including the same for inhibiting human 11-β-hydroxy steroid dehydrogenase type 1 (11β-HSD1) are excellent in activity and solubility, and is more efficient in formulation and transfer.
Public/Granted literature
Information query
