Invention Grant
US09073906B2 Sulfamide derivative having an adamantyl group and its pharmaceutically acceptable salt
有权
具有金刚烷基的磺酰胺衍生物及其药学上可接受的盐
- Patent Title: Sulfamide derivative having an adamantyl group and its pharmaceutically acceptable salt
- Patent Title (中): 具有金刚烷基的磺酰胺衍生物及其药学上可接受的盐
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Application No.: US14008899Application Date: 2012-03-30
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Publication No.: US09073906B2Publication Date: 2015-07-07
- Inventor: Ki Young Kim , Jin Hee Ahn , Seung Kyu Kang , Sang Dal Rhee , Myung Ae Bae , Sung Hoon Ahn , Hee Youn Kim , Won Hoon Jung , Nam Sook Kang
- Applicant: Ki Young Kim , Jin Hee Ahn , Seung Kyu Kang , Sang Dal Rhee , Myung Ae Bae , Sung Hoon Ahn , Hee Youn Kim , Won Hoon Jung , Nam Sook Kang
- Applicant Address: KR Daejeon
- Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- Current Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- Current Assignee Address: KR Daejeon
- Agency: Ladas & Parry LLP
- Priority: KR10-2011-0029829 20110331; KR10-2012-0004235 20120113
- International Application: PCT/KR2012/002407 WO 20120330
- International Announcement: WO2012/134233 WO 20121004
- Main IPC: C07D285/16
- IPC: C07D285/16 ; C07D285/36 ; A61K31/541 ; C07D417/04 ; A61K31/18 ; C07C307/10 ; C07D417/10 ; C07D417/12 ; C07D285/10 ; C07D285/14 ; C07D285/15
Abstract:
Provided is a sulfamide derivative having an adamantyl group represented by the following Formula 1, or a pharmaceutically acceptable salt thereof. The sulfamide derivative suppresses the activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), and is useful in the treatment of various diseases that are mediated by 11β-HSD1.
Public/Granted literature
- US20140024636A1 SULFAMIDE DERIVATIVE HAVING AN ADAMANTYL GROUP AND ITS PHARMACEUTICALLY ACCEPTABLE SALT Public/Granted day:2014-01-23
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