Invention Grant
- Patent Title: Anti-cancer compound and pharmaceutical composition containing the same
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Application No.: US13320965Application Date: 2010-05-17
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Publication No.: US09073917B2Publication Date: 2015-07-07
- Inventor: Jean-Christophe Carry , Michel Cheve , Francois Clerc , Cecile Combeau , Sylvie Gontier , Alain Krick , Sylvette Lachaud , Laurent Schio
- Applicant: Jean-Christophe Carry , Michel Cheve , Francois Clerc , Cecile Combeau , Sylvie Gontier , Alain Krick , Sylvette Lachaud , Laurent Schio
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Agency: Morrison & Foerster LLP
- Priority: FR0902392 20090518
- International Application: PCT/FR2010/050948 WO 20100517
- International Announcement: WO2010/133794 WO 20101125
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; A61P35/00 ; C07D405/12 ; C07D471/04 ; C07D235/26

Abstract:
The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of 0.698 mg/ml in methanol. The compound may be in the form of a base or an acid addition salt, in particular a pharmaceutically acceptable acid. The compound is a selective Aurora A and B kinase inhibitor and can be used as an anticancer drug.
Public/Granted literature
- US20120220621A1 ANTI-CANCER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Public/Granted day:2012-08-30
Information query
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