Invention Grant
- Patent Title: ND2 peptides and methods of treating neurological disease
- Patent Title (中): ND2肽和治疗神经疾病的方法
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Application No.: US13842848Application Date: 2013-03-15
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Publication No.: US09073976B2Publication Date: 2015-07-07
- Inventor: Michael Tymianski , Rongwen Li , Jonathan David Garman
- Applicant: NoNO Inc.
- Applicant Address: CA
- Assignee: NoNO Inc.
- Current Assignee: NoNO Inc.
- Current Assignee Address: CA
- Agency: Alston & Bird LLP
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C12N9/02 ; C07K7/06 ; A61K38/00
Abstract:
The invention is based in part on identifying a core region of ND2 responsible for interacting with Src to within residues 289-321 of ND2 and more particularly residues 307-321 or 310-321 of ND2. Peptides including, overlapping or from within this region can be used to inhibit ND2 interaction with Src Inhibition of this interaction is useful for treatment or prophylaxis of neurological diseases and disorders, pain and cancer.
Public/Granted literature
- US20140274906A1 ND2 PEPTIDES AND METHODS OF TREATING NEUROLOGICAL DISEASE Public/Granted day:2014-09-18
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