Invention Grant
- Patent Title: Tuberculosis TB vaccine to prevent reactivation
- Patent Title (中): 结核病结核病疫苗，以防止重新激活
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Application No.: US13262914Application Date: 2010-04-23
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Publication No.: US09074001B2Publication Date: 2015-07-07
- Inventor: Jes Dietrich , Peter Andersen , Carina Vingsbo Lundberg , Truc Thi Kim Than Hoang
- Applicant: Jes Dietrich , Peter Andersen , Carina Vingsbo Lundberg , Truc Thi Kim Than Hoang
- Applicant Address: DK
- Assignee: STATENS SERUM INSTITUT
- Current Assignee: STATENS SERUM INSTITUT
- Current Assignee Address: DK
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: DK200900539 20090424
- International Application: PCT/DK2010/000054 WO 20100423
- International Announcement: WO2010/121618 WO 20101028
- Main IPC: A61K39/04
- IPC: A61K39/04 ; A61K49/00 ; A61K39/00 ; C07K14/35
Abstract:
The present invention discloses a vaccine or immunogenic composition that can be administered to latently infected individuals to prevent reactivation of latent tuberculosis infection caused by species of the tuberculosis complex microorganisms (Mycobacterium tuberculosis, M. bovis, M. africanum). The invention is base on a number of M. tuberculosis derived proteins and protein fragments which are constitutively expressed in different stages of the infection. The invention is directed to the use of these polypeptides, immunologically active fragments thereof and the genes encoding them for immunological compositions such as vaccines.
Public/Granted literature
- US20120039925A1 TUBERCULOSIS TB VACCINE TO PREVENT REACTIVATION Public/Granted day:2012-02-16
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