Invention Grant
US09075044B2 Compositions and methods for detection and modulation of T cell mediated immune responses against viral vectors utilized for gene therapy
有权
用于检测和调节用于基因治疗的病毒载体的T细胞介导的免疫应答的组合物和方法
- Patent Title: Compositions and methods for detection and modulation of T cell mediated immune responses against viral vectors utilized for gene therapy
- Patent Title (中): 用于检测和调节用于基因治疗的病毒载体的T细胞介导的免疫应答的组合物和方法
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Application No.: US12302206Application Date: 2007-05-31
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Publication No.: US09075044B2Publication Date: 2015-07-07
- Inventor: Katherine A. High , Marcela V. Maus , Federico Mingozzi , Daniel J. Hui
- Applicant: Katherine A. High , Marcela V. Maus , Federico Mingozzi , Daniel J. Hui
- Applicant Address: US PA Philadelphia
- Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee Address: US PA Philadelphia
- Agency: Dann, Dorfman, Herrell & Skillman
- Agent Kathleen D. Rigaut; Robert C. Netter, Jr.
- International Application: PCT/US2007/070147 WO 20070531
- International Announcement: WO2007/140474 WO 20071206
- Main IPC: C07K7/06
- IPC: C07K7/06 ; G01N33/50 ; C07K14/725 ; A61K38/00
Abstract:
Compositions and methods are provided for inhibiting T cell mediated destruction of virally transduced, trangene containing cells.
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