An inventory monitoring controller maintains information reflecting a current inventory of articles based on radio frequency identification (RFID) tag identifying information received from one or more RFID tag readers in the context of inventory polling operations. In an embodiment, the controller also adjusts an operational parameter (e.g., a missing article detection threshold or a variable polling parameter) based on an analysis of the RFID tag identifying information. For example, a variable polling parameter may be adjusted in response to an occurrence of a triggering event (e.g., an inventory change indicated by the RFID tag identifying information or an occurrence of a temporal event), and a missing article detection threshold may be adjusted based on historical information relating to the detection of (or failure to detect) a particular RFID tag.