Invention Grant
- Patent Title: Heteroaryl sodium channel inhibitors
- Patent Title (中): 杂芳基钠通道抑制剂
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Application No.: US14238816Application Date: 2012-08-16
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Publication No.: US09079902B2Publication Date: 2015-07-14
- Inventor: Thomas Dineen , Isaac E Marx , Hanh Nho Nguyen , Matthew Weiss
- Applicant: Thomas Dineen , Isaac E Marx , Hanh Nho Nguyen , Matthew Weiss
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- International Application: PCT/US2012/051100 WO 20120816
- International Announcement: WO2013/025883 WO 20130221
- Main IPC: C07D209/04
- IPC: C07D209/04 ; C07D471/04 ; C07D403/14 ; C07D417/12 ; C07D417/14
Abstract:
The present invention provides compounds of Formula I or II, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
Public/Granted literature
- US20140256707A1 Heteroaryl Sodium Channel Inhibitors Public/Granted day:2014-09-11
Information query
