Invention Grant
US09084762B2 T-cell immunogens derived from anti-viral proteins and methods of using same 有权
衍生自抗病毒蛋白质的T细胞免疫原及其使用方法

T-cell immunogens derived from anti-viral proteins and methods of using same
Abstract:
Isolated polypeptides related to endogenous anti-viral polypeptides; and compositions, including immunogenic compositions, comprising a subject isolated polypeptide are disclosed herein. A subject isolated polypeptide comprises an amino acid sequence having substantial amino acid sequence identity to a contiguous stretch of amino acids of one or more endogenous anti-viral polypeptides, wherein the endogenous anti-viral polypeptides are polypeptides subject to proteolytic degradation as a result of the activity of one or more viral proteins. Also provided are diagnostic and treatment methods using the subject isolated polypeptides and compositions.
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