Invention Grant
- Patent Title: Fatty acid synthase inhibitors
- Patent Title (中): 脂肪酸合酶抑制剂
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Application No.: US14238418Application Date: 2012-08-16
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Publication No.: US09084794B2Publication Date: 2015-07-21
- Inventor: Jonathan Michael Ghergurovich , Michael Lee Moore , Cynthia Ann Parrish , Lance Howard Ridgers , Hongyi Lu
- Applicant: Jonathan Michael Ghergurovich , Michael Lee Moore , Cynthia Ann Parrish , Lance Howard Ridgers , Hongyi Lu
- Applicant Address: GB Brentord, Middlesex
- Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
- Current Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
- Current Assignee Address: GB Brentord, Middlesex
- Agent Wayne J. Dustman; Edward R. Gimmi
- International Application: PCT/US2012/051064 WO 20120816
- International Announcement: WO2013/028447 WO 20130228
- Main IPC: C07D498/10
- IPC: C07D498/10 ; A61K31/5386 ; A61K45/06
Abstract:
This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer.
Public/Granted literature
- US20140194415A1 FATTY ACID SYNTHASE INHIBITORS Public/Granted day:2014-07-10
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