Invention Grant
- Patent Title: Resin assisted capture of cysteine-modified proteins/peptides and determination of presence and location of modification
- Patent Title (中): 树脂辅助捕获半胱氨酸修饰的蛋白质/肽和确定修饰的存在和位置
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Application No.: US12745005Application Date: 2008-12-10
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Publication No.: US09086411B2Publication Date: 2015-07-21
- Inventor: Jonathan Stamler , Michael Forrester , Matthew Foster
- Applicant: Jonathan Stamler , Michael Forrester , Matthew Foster
- Applicant Address: US NC Durham
- Assignee: DUKE UNIVERSITY
- Current Assignee: DUKE UNIVERSITY
- Current Assignee Address: US NC Durham
- Agency: Bacon & Thomas, PLLC
- International Application: PCT/US2008/013538 WO 20081210
- International Announcement: WO2009/085106 WO 20090709
- Main IPC: G01N33/68
- IPC: G01N33/68 ; C07K1/16 ; G01N33/548 ; C07K1/107 ; C07K1/113 ; C07K1/13 ; C07K1/22 ; C08H1/00 ; G01N33/543
Abstract:
A resin connected by amide bond to pyridyl sulfide or methylthiosulfonate can be conjugated to a post traditionally modified protein/peptide to allow determination of presence and kind and optionally location of cysteine modification(s).
Public/Granted literature
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