At least one example embodiment discloses a method of reducing crosstalk interference in a system having a plurality of communication paths. The method includes obtaining a plurality of signal values corresponding to a set of active communication paths, the active communication paths being a subset of the plurality of communication paths, obtaining an inverse channel matrix, the inverse channel matrix representing an inverse crosstalk channel matrix of the system when the plurality of communication paths in the system are active, determining a plurality of sub-matrices from the inverse channel matrix based on the set of active communication paths and compensating the signal values for crosstalk by individually applying at least one of the sub-matrices to the plurality of signal values.