An orthodontic toothbrush comprising a handle, an attached head, and a plurality of bristles. The bristles define at least one well having the shorter length bristles at the center or bottom of the well and relatively longer length bristles bordering the wells. The wells are preferably spaced at the average distance between orthodontic braces. A plurality of bristles off the longitudinal plane of the toothbrush head are angled or slanted toward the toothbrush head median longitudinal plane, while another plurality of bristles are perpendicular to the toothbrush head plane. The well accommodates an orthodontic bracket or brace wherein the shortest bristles in the well clean the archwire and face of the orthodontic bracket and the relatively longer bristles clean under the wings of the bracket, the sides and rear of brackets and the teeth.