Invention Grant
US09095512B2 Method for producing spherical base granules comprising hardly water-soluble drug
有权
制备几乎不含水溶性药物的球形基础颗粒的方法
- Patent Title: Method for producing spherical base granules comprising hardly water-soluble drug
- Patent Title (中): 制备几乎不含水溶性药物的球形基础颗粒的方法
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Application No.: US12310067Application Date: 2007-08-09
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Publication No.: US09095512B2Publication Date: 2015-08-04
- Inventor: Yoshihito Yaginuma , Rika Matsumoto
- Applicant: Yoshihito Yaginuma , Rika Matsumoto
- Applicant Address: JP Tokyo
- Assignee: ASAHI KASEI CHEMICALS CORPORATION
- Current Assignee: ASAHI KASEI CHEMICALS CORPORATION
- Current Assignee Address: JP Tokyo
- Agency: Staas & Halsey LLP
- Priority: JP2006-220247 20060811
- International Application: PCT/JP2007/065654 WO 20070809
- International Announcement: WO2008/018561 WO 20080214
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K9/16 ; A61K31/166 ; A01N43/56 ; A61K9/14
Abstract:
Spherical base granules comprising a hardly water-soluble drug and suited for film coating thereon are produced by layering spherical core particles with a drug-containing layering liquid comprising both micronized microcrystalline cellulose and an emulsifier therein and therefore having improved suspension stability.
Public/Granted literature
- US20090324802A1 METHOD FOR PRODUCING SPHERICAL BASE GRANULES COMPRISING HARDLY WATER-SOLUBLE DRUG Public/Granted day:2009-12-31
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