Invention Grant
- Patent Title: GABA release-regulating agent in cerebellum
- Patent Title (中): GABA释放调节剂在小脑中
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Application No.: US13389981Application Date: 2010-08-24
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Publication No.: US09095535B2Publication Date: 2015-08-04
- Inventor: Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
- Applicant: Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
- Applicant Address: KR Seoul
- Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul
- Agency: Goldilocks ZONE IP LAW
- Priority: KR10-2009-0077979 20090824
- International Application: PCT/KR2010/005653 WO 20100824
- International Announcement: WO2011/025230 WO 20110303
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61P25/00 ; A61P25/28 ; A61P25/32 ; A61P25/08 ; G01R27/28 ; A61K31/00 ; A61K31/185 ; A61K31/196 ; A61K31/455 ; A61K31/7105 ; A61K31/713 ; A61K38/04 ; A61K38/08 ; G01N33/94
Abstract:
A GABA (gamma-aminobutyric acid) release-inhibiting agent in the cerebellum and a composition for treating pathological symptoms caused by over-release of GABA in the cerebellum, each comprising a Bestrophin 1 (Best1) channel inhibitor as an active ingredient; a GABA release-promoting agent in the cerebellum and a composition for treating pathological symptoms caused by the deficit of GABA in the cerebellum, each comprising a Best1 channel activator as an active ingredient; and a method for screening a GABA release-regulating agent in the cerebellum, which uses Best1 channel as target, are provided.
Public/Granted literature
- US20120214742A1 GABA RELEASE-REGULATING AGENT IN CEREBELLUM Public/Granted day:2012-08-23
Information query
