Invention Grant
US09095573B2 Method of biasing implanted human neural stem cells away from differentiation into glial cells by (+)phenserine to modulate the concentration of soluble βAPP in tissue or CSF
有权
通过（+）苯丝氨酸将植入的人神经干细胞偏离成分化为神经胶质细胞的方法来调节组织或CSF中可溶性和浓度的APP的浓度
- Patent Title: Method of biasing implanted human neural stem cells away from differentiation into glial cells by (+)phenserine to modulate the concentration of soluble βAPP in tissue or CSF
- Patent Title (中): 通过（+）苯丝氨酸将植入的人神经干细胞偏离成分化为神经胶质细胞的方法来调节组织或CSF中可溶性和浓度的APP的浓度
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Application No.: US11461631Application Date: 2006-08-01
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Publication No.: US09095573B2Publication Date: 2015-08-04
- Inventor: Kiminobu Sugaya , Amelia Marutle , Young Don Kwak
- Applicant: Kiminobu Sugaya , Amelia Marutle , Young Don Kwak
- Assignee: University of Central Florida Research Foundation, Inc.
- Current Assignee: University of Central Florida Research Foundation, Inc.
- Agency: Beusse, Wolter, Sanks & Maire, P.A.
- Agent Timothy H. Van Dyke
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A01N63/00 ; C12N5/00 ; C12N5/079 ; C12N5/0797 ; C12N5/0735 ; C12N5/074 ; C12N5/071 ; A61K31/407 ; A61K35/12
Abstract:
Disclosed herein are methods and materials for promoting neurogenesis of endogenous and transplanted stem cells. Specifically exemplified herein are methods that comprise transplanting neural stem cells in conjunction with a regimen of (+)phenserine treatment.
Public/Granted literature
- US20070071731A1 Promotion Of Neurogenesis Of Endogenous And Transplanted Human Neural Stem Cells Public/Granted day:2007-03-29
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