Invention Grant
US09095599B2 O-(substituted benzyl) phosphoramidate compounds and therapeutic use
有权
O-（取代苄基）氨基磷酸酯化合物和治疗用途
- Patent Title: O-(substituted benzyl) phosphoramidate compounds and therapeutic use
- Patent Title (中): O-（取代苄基）氨基磷酸酯化合物和治疗用途
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Application No.: US13978272Application Date: 2011-12-30
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Publication No.: US09095599B2Publication Date: 2015-08-04
- Inventor: Junbiao Chang , Zheng Wang , Suping Zhou
- Applicant: Junbiao Chang , Zheng Wang , Suping Zhou
- Applicant Address: CN Nanjing
- Assignee: Nanjing Molecular Research, Inc.
- Current Assignee: Nanjing Molecular Research, Inc.
- Current Assignee Address: CN Nanjing
- Agency: Fox Rothschild LLP
- Agent Wansheng Jerry Liu
- International Application: PCT/US2011/068131 WO 20111230
- International Announcement: WO2012/094248 WO 20120712
- Main IPC: A61K31/7076
- IPC: A61K31/7076 ; A61K31/706 ; A61K31/7068 ; A61K31/7072 ; A61K45/06 ; C07H19/10 ; C07H19/20 ; C07H19/12 ; A61K31/075 ; C07F9/6558 ; C07F9/6561
Abstract:
This application discloses novel phosphoramidate and phosphonoamidate prodrugs of nucleosides, nucleotides, C-nucleosides, C-nucleotides, phosphonates, and other alcohol-containing drugs; use of these prodrugs for treatment of infectious diseases and cancers, in particular, liver infections and cancers; and methods of preparing these novel phosphoramidate and phosphonoamidate prodrugs.
Public/Granted literature
- US20140038916A1 O-(SUBSTITUTED BENZYL) PHOSPHORAMIDATE COMPOUNDS AND THERAPEUTIC USE Public/Granted day:2014-02-06
Information query
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