Invention Grant
US09095618B2 Conjugates of a polymer, a bisphosphonate and an anti-angiogenesis agent and uses thereof in the treatment and monitoring of bone related diseases
有权
聚合物，双膦酸盐和抗血管生成剂的结合物及其在治疗和监测骨相关疾病中的用途
- Patent Title: Conjugates of a polymer, a bisphosphonate and an anti-angiogenesis agent and uses thereof in the treatment and monitoring of bone related diseases
- Patent Title (中): 聚合物，双膦酸盐和抗血管生成剂的结合物及其在治疗和监测骨相关疾病中的用途
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Application No.: US14158881Application Date: 2014-01-20
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Publication No.: US09095618B2Publication Date: 2015-08-04
- Inventor: Ronit Satchi-Fainaro , Keren Miller , Doron Shabat , Rotem Erez
- Applicant: Ramot at Tel-Aviv University Ltd.
- Applicant Address: IL Tel-Aviv
- Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee: Ramot at Tel-Aviv University Ltd.
- Current Assignee Address: IL Tel-Aviv
- Main IPC: A61K31/74
- IPC: A61K31/74 ; A61K47/48 ; C07F9/38 ; C07F9/655 ; C07F9/6558 ; C07K5/065 ; C07K5/103 ; A61K31/337 ; A61K49/00 ; A61K9/16
Abstract:
Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed.Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.
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