Invention Grant
- Patent Title: Acyl sulfonamide compounds
- Patent Title (中): 酰基磺酰胺化合物
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Application No.: US13808639Application Date: 2011-07-04
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Publication No.: US09096500B2Publication Date: 2015-08-04
- Inventor: Alan Daniel Brown , David James Rawson , Robert Ian Storer , Nigel Alan Swain
- Applicant: Alan Daniel Brown , David James Rawson , Robert Ian Storer , Nigel Alan Swain
- Applicant Address: GB Sandwich
- Assignee: Pfizer Limited
- Current Assignee: Pfizer Limited
- Current Assignee Address: GB Sandwich
- Agent J. Michael Dixon
- International Application: PCT/IB2011/052940 WO 20110704
- International Announcement: WO2012/007868 WO 20120119
- Main IPC: C07C311/04
- IPC: C07C311/04 ; A61K31/18 ; C07C311/51 ; C07D231/12 ; A61K31/277 ; A61K31/415 ; A61K31/4245 ; A61K31/451 ; A61K31/495 ; A61K31/50 ; A61K45/06 ; C07D211/22 ; C07D237/08 ; C07D241/04 ; C07D271/06

Abstract:
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein X, Ar1, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
Public/Granted literature
- US20130109701A1 Chemical Compounds Public/Granted day:2013-05-02
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