Invention Grant
US09096501B2 Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
有权
纤溶酶原激活物抑制剂-1抑制剂及其用于调节脂质代谢的方法
- Patent Title: Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism
- Patent Title (中): 纤溶酶原激活物抑制剂-1抑制剂及其用于调节脂质代谢的方法
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Application No.: US14284021Application Date: 2014-05-21
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Publication No.: US09096501B2Publication Date: 2015-08-04
- Inventor: Daniel A. Lawrence , Dudley Strickland , Jacqueline Cale , Enming Joe Su , Cory Emal , Mark Warnock
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor US MD Baltimore US MI Ypsilanti
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,UNIVERSITY OF MARYLAND, BALTIMORE,EASTERN MICHIGAN UNIVERSITY
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN,UNIVERSITY OF MARYLAND, BALTIMORE,EASTERN MICHIGAN UNIVERSITY
- Current Assignee Address: US MI Ann Arbor US MD Baltimore US MI Ypsilanti
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: C07C311/29
- IPC: C07C311/29 ; C07C69/88 ; C07C271/22 ; C07H13/08 ; G01N33/92
Abstract:
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
Public/Granted literature
- US20140343321A1 Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism Public/Granted day:2014-11-20
Information query
