Invention Grant
- Patent Title: Substituted hydroxamic acids and uses thereof
- Patent Title (中): 取代的异羟肟酸及其用途
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Application No.: US12803169Application Date: 2010-06-21
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Publication No.: US09096518B2Publication Date: 2015-08-04
- Inventor: Christopher Blackburn , Jeffrey P. Ciavarri , Kenneth M. Gigstad , He Xu
- Applicant: Christopher Blackburn , Jeffrey P. Ciavarri , Kenneth M. Gigstad , He Xu
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Millennium Pharmaceuticals, Inc.
- Main IPC: C07D217/16
- IPC: C07D217/16 ; A61K31/47 ; C07D209/44 ; C07D217/04 ; C07D217/06 ; C07D217/08 ; C07D223/16 ; C07D225/06 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D401/12 ; C07D403/04 ; C07D403/06 ; C07D405/06 ; C07D405/12 ; C07D409/06 ; C07D409/12 ; C07D413/06 ; C07D413/12 ; C07D413/14 ; C07D417/04 ; C07D417/06 ; C07D417/14 ; C07D491/04
Abstract:
This invention provides compounds of formula (I) wherein R1, R2, G, m, n, p and q have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
Public/Granted literature
- US20110039827A1 Substituted hydroxamic acids and uses thereof Public/Granted day:2011-02-17
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