Invention Grant
US09096601B2 Arylamino purine derivatives, preparation method and pharmaceutical use thereof
有权
芳基氨基嘌呤衍生物，其制备方法和药物用途
- Patent Title: Arylamino purine derivatives, preparation method and pharmaceutical use thereof
- Patent Title (中): 芳基氨基嘌呤衍生物，其制备方法和药物用途
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Application No.: US13699960Application Date: 2010-12-23
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Publication No.: US09096601B2Publication Date: 2015-08-04
- Inventor: Shengyong Yang , Yuquan Wei
- Applicant: Shengyong Yang , Yuquan Wei
- Applicant Address: CN Shijiazhuang, Hebei Province CN Chengdu, Sichuan Province
- Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.,Sichuan University
- Current Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.,Sichuan University
- Current Assignee Address: CN Shijiazhuang, Hebei Province CN Chengdu, Sichuan Province
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: CN201010184478 20100526
- International Application: PCT/CN2010/002126 WO 20101223
- International Announcement: WO2011/147066 WO 20111201
- Main IPC: C07D473/16
- IPC: C07D473/16 ; C07D473/18 ; C07D473/32
Abstract:
Arylamino purine derivatives represented by formula I and their preparation method are disclosed, wherein each substituent is defined as in the description. The derivatives have an inhibitory effect on non-small cell lung cancer with deletion mutation of exon 19 or L858R point mutation of exon 21 in epidermal growth factor receptor (EGFR).
Public/Granted literature
- US20130203986A1 Arylamino Purine Derivatives, Preparation Method and Pharmaceutical Use Thereof Public/Granted day:2013-08-08
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