Invention Grant
- Patent Title: Tumor necrosis factor inhibitors
- Patent Title (中): 肿瘤坏死因子抑制剂
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Application No.: US14279506Application Date: 2014-05-16
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Publication No.: US09096607B2Publication Date: 2015-08-04
- Inventor: Mark I. Greene , Ramachandran Murali , Xin Cheng , Raphael Ottenbrite , Yingxin Xiao
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee: The Trustees Of The University Of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Baker & Hostetler LLP
- Main IPC: A61K31/15
- IPC: A61K31/15 ; C07D311/82 ; C07D493/10 ; C07C251/86 ; A61K31/352 ; A61K31/365
Abstract:
The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-α mediated conditions.
Public/Granted literature
- US20140256803A1 TUMOR NECROSIS FACTOR INHIBITORS Public/Granted day:2014-09-11
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