Invention Grant
US09096639B2 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases
有权
17-羟基-17-五氟乙基 - 雌-4,4（10） - 二烯-11-酰氧基亚烷基苯基衍生物，其制备方法和用于治疗疾病的用途
- Patent Title: 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases
- Patent Title (中): 17-羟基-17-五氟乙基 - 雌-4,4（10） - 二烯-11-酰氧基亚烷基苯基衍生物，其制备方法和用于治疗疾病的用途
-
Application No.: US13384332Application Date: 2010-07-07
-
Publication No.: US09096639B2Publication Date: 2015-08-04
- Inventor: Ulrich Klar , Wolfgang Schwede , Carsten Moller , Andrea Rotgeri , Ursula Krenz
- Applicant: Ulrich Klar , Wolfgang Schwede , Carsten Moller , Andrea Rotgeri , Ursula Krenz
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GmbH
- Current Assignee: Bayer Intellectual Property GmbH
- Current Assignee Address: DE Monheim
- Agent Karen B. King; Thomas C. Blankinship
- Priority: DE102009034368 20090720
- International Application: PCT/EP2010/004148 WO 20100707
- International Announcement: WO2011/009530 WO 20110127
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61K31/58 ; C07J11/00 ; C07J41/00 ; C07J1/00 ; C07J7/00 ; C07J43/00 ; A61K31/573
Abstract:
The invention relates to 17-hydroxy-13-methyl-17-pentafluoroethyl-11-acyloxyalkylenephenyldodecahydrocyclopenta[a]phenanthren-3-one derivatives of the formula I with progesterone-antagonizing action and to processes for preparation thereof, to use thereof for treatment and/or prophylaxis of disorders and to the use thereof for production of medicaments for treatment and/or prophylaxis of disorders, especially of fibroids of the uterus (myomas, uterine leiomyomas), endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause, or for fertility control and emergency contraception.
Public/Granted literature
Information query
