Invention Grant
US09096653B2 Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia
有权
用于疟疾的多组分疫苗提供对疟原虫的持久免疫反应
- Patent Title: Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia
- Patent Title (中): 用于疟疾的多组分疫苗提供对疟原虫的持久免疫反应
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Application No.: US13870547Application Date: 2013-04-25
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Publication No.: US09096653B2Publication Date: 2015-08-04
- Inventor: Rachel Schneerson , Joanna Kubler-Kielb , John B. Robbins , Fathy Majadly , Christopher P. Mocca , Jerry Keith , Zuzana Biesova , Louis Miller , Ruth Nussenzweig , Darrell T. Liu
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services , New York University
- Applicant Address: US DC Washington US NY New York
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,New York University
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,New York University
- Current Assignee Address: US DC Washington US NY New York
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K39/385
- IPC: A61K39/385 ; A61K39/015 ; C07K14/00 ; A61K47/48
Abstract:
Disclosed are immunogenic conjugates which elicit an immune response to Plasmodium proteins. In particular examples, the Plasmodium proteins include sexual stage surface proteins, circumsporozoite protein (CSP), or immunogenic portions of CSP. Also provided herein are immunogenic compositions including one or more of the disclosed immunogenic conjugates and a pharmaceutically acceptable carrier. Further provided is a method of eliciting an immune response to Plasmodium in a subject, comprising administering to the subject an immunogenic composition disclosed herein.
Public/Granted literature
- US20130216570A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA Public/Granted day:2013-08-22
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