Invention Grant
US09096659B2 Flagellin fusion proteins and use thereof to induce immune responses against Pseudomonas aeruginosa
有权
鞭毛蛋白融合蛋白及其用于诱导针对铜绿假单胞菌的免疫应答
- Patent Title: Flagellin fusion proteins and use thereof to induce immune responses against Pseudomonas aeruginosa
- Patent Title (中): 鞭毛蛋白融合蛋白及其用于诱导针对铜绿假单胞菌的免疫应答
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Application No.: US13256882Application Date: 2010-03-16
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Publication No.: US09096659B2Publication Date: 2015-08-04
- Inventor: Steven B. Mizel , Daniel J. Wozniak , Eric T. Weimer
- Applicant: Steven B. Mizel , Daniel J. Wozniak , Eric T. Weimer
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Sciences
- Current Assignee: Wake Forest University Health Sciences
- Current Assignee Address: US NC Winston-Salem
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- International Application: PCT/US2010/027460 WO 20100316
- International Announcement: WO2010/107778 WO 20100923
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/12 ; A61K39/104 ; C07K14/21
Abstract:
The invention provides compositions and fusion proteins comprising a flagellin adjuvant and a Pseudomonas aeruginosa antigen. The invention further provides pharmaceutical formulations and methods for inducing an immune response against P. aeruginosa (e.g., to prevent and/or treat P. aeruginosa infection).
Public/Granted literature
- US20120064106A1 FLAGELLIN FUSION PROTEINS AND USE THEREOF TO INDUCE IMMUNE RESPONSES AGAINST PSEUDOMONAS AERUGINOSA Public/Granted day:2012-03-15
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