Invention Grant
US09096664B2 Nucleic acid encoding hepatocyte growth factor (HGF) binding proteins
有权
核酸编码肝细胞生长因子（HGF）结合蛋白
- Patent Title: Nucleic acid encoding hepatocyte growth factor (HGF) binding proteins
- Patent Title (中): 核酸编码肝细胞生长因子（HGF）结合蛋白
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Application No.: US14044278Application Date: 2013-10-02
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Publication No.: US09096664B2Publication Date: 2015-08-04
- Inventor: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
- Applicant: AVEO Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge US CA Berkeley
- Assignee: AVEO Pharmaceuticals, Inc.,Xoma Technologies, Ltd.
- Current Assignee: AVEO Pharmaceuticals, Inc.,Xoma Technologies, Ltd.
- Current Assignee Address: US MA Cambridge US CA Berkeley
- Agency: Goodwin Procter LLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/63 ; C12N5/12 ; C12N15/00 ; C07K16/22 ; A61K39/00
Abstract:
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Public/Granted literature
- US20140178935A1 HEPATOCYTE GROWTH FACTOR (HGF) BINDING PROTEINS Public/Granted day:2014-06-26
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