Invention Grant
US09096676B2 Antibodies to MASP-2 有权
MASP-2抗体

  • Patent Title: Antibodies to MASP-2
  • Patent Title (中): MASP-2抗体
  • Application No.: US10556509
    Application Date: 2004-05-12
  • Publication No.: US09096676B2
    Publication Date: 2015-08-04
  • Inventor: Flemming LarsenUlla Wahlers
  • Applicant: Flemming LarsenUlla Wahlers
  • Applicant Address: DK Copenhagen
  • Assignee: Helion Biotech APS
  • Current Assignee: Helion Biotech APS
  • Current Assignee Address: DK Copenhagen
  • Agent Tineka J. Quinton; Marcia S. Kelbon
  • Priority: DK200300716 20030512
  • International Application: PCT/DK2004/000338 WO 20040512
  • International Announcement: WO2004/106384 WO 20041209
  • Main IPC: C12P21/08
  • IPC: C12P21/08 C07K16/40
Antibodies to MASP-2
Abstract:
The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognizing said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
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