Invention Grant
- Patent Title: Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
- Patent Title (中): 针对结缔组织生长因子的反义寡核苷酸及其用途
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Application No.: US13532254Application Date: 2012-06-25
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Publication No.: US09096851B2Publication Date: 2015-08-04
- Inventor: Nicholas M. Dean , J. Gordon Foulkes , Niall O'Donnell , C. Frank Bennett , Susan M. Frier
- Applicant: Nicholas M. Dean , J. Gordon Foulkes , Niall O'Donnell , C. Frank Bennett , Susan M. Frier
- Applicant Address: US NY New York US CA Carlsbad
- Assignee: Excaliard Pharmaceuticals, Inc.,Isis Pharmaceuticals, Inc.
- Current Assignee: Excaliard Pharmaceuticals, Inc.,Isis Pharmaceuticals, Inc.
- Current Assignee Address: US NY New York US CA Carlsbad
- Agency: Lando & Anastasi, LLP
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12Q1/68
Abstract:
This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.
Public/Granted literature
- US20130190380A1 ANTISENSE OLIGONUCLEOTIDES DIRECTED AGAINST CONNECTIVE TISSUE GROWTH FACTOR AND USES THEREOF Public/Granted day:2013-07-25
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