Invention Grant
- Patent Title: Selection of RNA-aptamers as anti-malaria agents
- Patent Title (中): 选择RNA适体作为抗疟剂
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Application No.: US12866413Application Date: 2009-02-05
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Publication No.: US09096857B2Publication Date: 2015-08-04
- Inventor: Johan Lindh , Tina Persson
- Applicant: Johan Lindh , Tina Persson
- Applicant Address: SE Malmo
- Assignee: APTAHEM AB
- Current Assignee: APTAHEM AB
- Current Assignee Address: SE Malmo
- Agency: Brooks Kushman P.C.
- Priority: SE0800262 20080205
- International Application: PCT/SE2009/000072 WO 20090205
- International Announcement: WO2009/099378 WO 20090813
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61K31/7105 ; C12N15/115

Abstract:
The present invention relates to an aptamer or an active fragment thereof raised against the semi-conserved duffy binding ligand domain 1α, DBL1α, region of the Plasmodium falciparum erythrocyte membrane protein 1, PfEMPI, which aptamer has an effect against malaria, in particular severe cerebral malaria.
Public/Granted literature
- US20110003886A1 SELECTION OF RNA APTAMERS AS ANTI-MALARIA AGENTS Public/Granted day:2011-01-06
Information query
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