Invention Grant
- Patent Title: Method for determining lymph node metastasis in cancer or risk thereof and rapid determination kit for the same
- Patent Title (中): 确定癌症淋巴结转移或其风险的方法及其快速测定试剂盒
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Application No.: US13322537Application Date: 2010-05-27
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Publication No.: US09096904B2Publication Date: 2015-08-04
- Inventor: Satoru Motoyama , Masatomo Miura , Junichi Ogawa
- Applicant: Satoru Motoyama , Masatomo Miura , Junichi Ogawa
- Applicant Address: JP Akita-shi, Akita
- Assignee: NATIONAL UNIVERSITY CORPORATION AKITA UNIVERSITY
- Current Assignee: NATIONAL UNIVERSITY CORPORATION AKITA UNIVERSITY
- Current Assignee Address: JP Akita-shi, Akita
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2009-128323 20090527
- International Application: PCT/JP2010/059049 WO 20100527
- International Announcement: WO2010/137671 WO 20101202
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02
Abstract:
The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.
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