Systems and methods for managing cache configurations are disclosed. In accordance with a method, a system management control module may receive access rights of a host to a logical storage unit and may also receive a desired caching policy for caching data associated with the logical storage unit and the host. The system management control module may determine an allowable caching policy indicator for the logical storage unit. The allowable caching policy indicator may indicate whether caching is permitted for data associated with input/output operations between the host and the logical storage unit. The system management control module may further set a caching policy for data associated with input/output operations between the host and the logical storage unit, based on at least one of the desired caching policy and the allowable caching policy indicator. The system management control module may also communicate the caching policy to the host.