Cardiac tissue ablation is carried out by defining first regions containing first locations including ganglionated plexi in a heart of a living subject, and inserting a probe into the heart. The method is further carried out by detecting electrical activity in the heart via electrodes on the distal portion of the probe, defining second regions having second locations, wherein the electrical activity exhibits a dominant frequency that is higher than a predefined threshold, defining third regions having third locations, wherein the electrical activity exhibits complex fractionated atrial electrograms, constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the second regions and the third regions, selecting ablation sites within the intersections, and ablating cardiac tissue at the ablation sites.