Invention Grant
US09101609B2 CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
有权
CD37免疫治疗和与其双功能化学治疗组合
- Patent Title: CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
- Patent Title (中): CD37免疫治疗和与其双功能化学治疗组合
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Application No.: US12422780Application Date: 2009-04-13
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Publication No.: US09101609B2Publication Date: 2015-08-11
- Inventor: Philip Tan , Sandy A Simon , Charles G Cerveny , Christy Anne Nilsson , William Brady , Jeffrey A Ledbetter , Martha S Hayden-Ledbetter , Peter A Thompson , Cecile Morales
- Applicant: Philip Tan , Sandy A Simon , Charles G Cerveny , Christy Anne Nilsson , William Brady , Jeffrey A Ledbetter , Martha S Hayden-Ledbetter , Peter A Thompson , Cecile Morales
- Applicant Address: US WA Seattle
- Assignee: EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC
- Current Assignee: EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC
- Current Assignee Address: US WA Seattle
- Agency: Cooley LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; C07K16/28 ; A61K31/4184 ; C07K16/46 ; A61K38/16 ; A61K39/00
Abstract:
The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B-cell related autoimmune, inflammatory, or hyperproliferative diseases.
Public/Granted literature
- US20090274692A1 CD37 IMMUNOTHERAPEUTIC AND COMBINATION WITH BIFUNCTIONAL CHEMOTHERAPEUTIC THEREOF Public/Granted day:2009-11-05
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