Invention Grant
US09101643B2 Lipid formulated compositions and methods for inhibiting expression of transthyretin (TTR)
有权
脂质配制组合物和抑制转甲状腺素蛋白（TTR）表达的方法
- Patent Title: Lipid formulated compositions and methods for inhibiting expression of transthyretin (TTR)
- Patent Title (中): 脂质配制组合物和抑制转甲状腺素蛋白（TTR）表达的方法
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Application No.: US13503843Application Date: 2010-11-03
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Publication No.: US09101643B2Publication Date: 2015-08-11
- Inventor: Dinah Wen-Yee Sah
- Applicant: Dinah Wen-Yee Sah
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- International Application: PCT/US2010/055311 WO 20101103
- International Announcement: WO2011/056883 WO 20110512
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; A61K31/7088 ; A61K31/7115 ; A61K31/713 ; C12N15/113 ; C12Q1/68
Abstract:
The invention relates to lipid formulated double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Public/Granted literature
- US20120294905A1 Lipid Formulated Compositions And Methods For Inhibiting Expression Of Transthyretin (TTR) Public/Granted day:2012-11-22
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