Invention Grant
US09101646B2 Bispecific antisense oligonucleotides that inhibit IGFBP-2 and IGFBP-5 and methods of using same
有权
抑制IGFBP-2和IGFBP-5的双特异性反义寡核苷酸及其使用方法
- Patent Title: Bispecific antisense oligonucleotides that inhibit IGFBP-2 and IGFBP-5 and methods of using same
- Patent Title (中): 抑制IGFBP-2和IGFBP-5的双特异性反义寡核苷酸及其使用方法
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Application No.: US12752581Application Date: 2010-04-01
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Publication No.: US09101646B2Publication Date: 2015-08-11
- Inventor: Martin Gleave , Maxim Signaevsky
- Applicant: Martin Gleave , Maxim Signaevsky
- Applicant Address: CA Vancouver
- Assignee: The University of British Columbia
- Current Assignee: The University of British Columbia
- Current Assignee Address: CA Vancouver
- Agency: Larson & Anderson, LLC
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K31/713 ; C12N15/113 ; A61K38/00
Abstract:
Bispecific antisense oligonucleotides which consist essentially of a sequence of bases that is complementary to portions of both the gene encoding human IGFBP-2 and the gene encoding human IGFBP-5 are useful in as antisense therapeutics in the treatment of endocrine-regulated cancers.
Public/Granted literature
- US20100267808A1 Bispecific Antisense Oligonucleotides that Inhibit IGFBP-2 and IGFBP-5 and Methods of Using Same Public/Granted day:2010-10-21
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